Description

1-Phenyl-3-Chloro-1-Propyne is a versatile halogenated alkyne building block with significant utility in advanced organic synthesis. Its unique structure, featuring both a phenyl group and a reactive chloroalkyne moiety, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to introduce functionalized acetylene units into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the preparation of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne linkages or as a precursor for heterocyclic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate acetylene-based functional groups for enhanced activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers, dendrimers, and advanced organic materials with tailored electronic or mechanical properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel alkynyl-based ligands for transition metal catalysis and organometallic chemistry applications.
• Chemical Biology Probes: Utilized in click chemistry and bioorthogonal labeling strategies to tag biomolecules due to its reactive alkyne handle.
• Fine Chemical Production: A crucial building block for manufacturing complex fragrance compounds, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	1-Phenyl-3-Chloro-1-Propyne
CAS No.	3355-31-5
Molecular Formula	C9H7Cl
Molecular Weight	150.60 g/mol
Synonyms	3-Chloro-1-phenyl-1-propyne; 1-Phenyl-3-chloroprop-1-yne; (3-Chloroprop-1-yn-1-yl)benzene; 3-Chloro-1-phenylpropyne; Benzene, (3-chloro-1-propyn-1-yl)-; Chloromethyl phenylacetylene; Phenylchloropropyne; 1-Chloro-3-phenyl-2-propylene
EINECS	Contact for details

Quality Control

Our 1-Phenyl-3-Chloro-1-Propyne is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.550 - 1.560
Density (g/mL, 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.