Description

Amidephrine is a synthetic organic compound belonging to the class of sympathomimetic amines. This compound is valued for its specific pharmacological activity profile, making it a key intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of specialized adrenergic agents and other therapeutic compounds.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies targeting adrenergic receptors.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in custom synthesis projects.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP and non-GMP production runs.

Basic Information

Product Name	Amidephrine
CAS No.	3354-67-4
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	2-[(2,5-Dimethoxyphenyl)amino]-2-imidazoline; Amidephrine; Amidefrin; FLA 136; McN 1230; Midodrin Impurity; (2,5-Dimethoxyphenyl)amino-2-imidazoline
EINECS	222-128-8

Quality Control

Our Amidephrine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and purity, and identification by FTIR and NMR. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.