Description

1-(4-Bromophenyl)-2-Hydroxyethan-1-One is a versatile brominated aromatic ketone that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a ketone and a benzylic hydroxyl group adjacent to a bromine-substituted aromatic ring, makes it a valuable precursor for constructing complex pharmaceutical intermediates and specialty chemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the bromophenyl moiety for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and metal-organic complexes used in asymmetric catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Research & Development: A versatile starting material for heterocyclic chemistry, including the synthesis of benzofurans and indoles.
• Fine Chemical Production: Utilized in the custom synthesis of specialty dyes, pigments, and UV absorbers.

Basic Information

Product Name	1-(4-Bromophenyl)-2-Hydroxyethan-1-One
CAS No.	3343-45-1
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	4'-Bromo-2-hydroxyacetophenone; 2-Hydroxy-1-(4-bromophenyl)ethanone; 1-(4-Bromophenyl)-2-hydroxyethanone; p-Bromophenacyl alcohol; 4-Bromophenacyl alcohol; 2-Hydroxy-4'-bromoacetophenone; 4-Bromo-2-hydroxyacetophenone; α-Hydroxy-4-bromoacetophenone
EINECS	222-104-9

Quality Control

Our production of 1-(4-Bromophenyl)-2-Hydroxyethan-1-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide Certificates of Analysis (COA) with every shipment, detailing all critical parameters to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.