Description

Tetrahydro-Thiophen-3-Ol is a versatile sulfur-containing heterocyclic alcohol with significant utility in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of pharmaceuticals, agrochemicals, and specialty chemicals. Key industries that rely on this high-purity intermediate include pharmaceutical R&D, flavor and fragrance manufacturing, and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in thiophene-based drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the thiophene moiety imparts specific biological activity.
• Flavor & Fragrance Ingredient: Acts as a precursor for sulfur-containing flavor compounds, contributing to meaty, roasted, or savory notes in food products and perfumery.
• Ligand & Catalyst Preparation: Employed in the development of specialized ligands for asymmetric catalysis and metal complexation.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of novel polymers and functional materials.
• Organic Synthesis Building Block: Utilized in various name reactions and cyclization processes to construct complex molecular architectures.

Basic Information

Product Name	Tetrahydro-Thiophen-3-Ol
CAS No.	3334-05-2
Molecular Formula	C4H8OS
Molecular Weight	104.17 g/mol
Synonyms	3-Hydroxytetrahydrothiophene; Tetrahydro-3-thiophenol; 3-Thiophenemethanol, tetrahydro-; 3-Thiophanemethanol; 3-Tetrahydrothienyl alcohol; 3-Hydroxythiolane; THT-3-ol; Tetrahydrothiophen-3-yl alcohol
EINECS	222-065-9

Quality Control

Our Tetrahydro-Thiophen-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.520 - 1.530
Specific Gravity (20°C)	1.150 - 1.180

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.