Description

2-Diazocyclohexanone is a versatile and highly reactive diazo compound, primarily valued as a key intermediate in organic synthesis for the construction of complex molecular frameworks. Its importance stems from its ability to undergo a range of transformations, including cyclopropanation, X-H insertion, and Wolff rearrangement reactions, enabling efficient synthesis of strained and functionalized carbocycles. This makes it a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug molecules, particularly those containing cyclopropane or other strained ring systems.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where its reactivity is leveraged to create unique bioactive structures.
• Catalyst and Ligand Development: Acts as a precursor for the synthesis of specialized metal-carbene complexes used in catalysis.
• Polymer and Material Science: Employed in the creation of novel polymers and advanced materials with tailored properties via cyclopropanation reactions.
• Organic Methodology Research: A standard reagent in academic and industrial R&D for developing new synthetic methodologies involving diazo compounds.
• Fine Chemical Production: Utilized in the multistep synthesis of high-value, low-volume specialty chemicals and flavors & fragrances.

Basic Information

Product Name	2-Diazocyclohexanone
CAS No.	3242-56-6
Molecular Formula	C6H8N2O
Molecular Weight	124.14 g/mol
Synonyms	2-Diazo-cyclohexanone; 2-Diazo-1-cyclohexanone; Cyclohexanone, 2-diazo-; 2-Diazocyclohexan-1-one; α-Diazocyclohexanone; 2-Diazo-cyclohexanon; Diazocyclohexanone
EINECS	221-824-6

Quality Control

Our 2-Diazocyclohexanone is produced under stringent quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality management system is designed to meet the rigorous demands of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or solution
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Solvent Content (GC)	As per COA (if supplied in solution)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.