Description

2-Hydroxy-2-Isopropylsuccinic Acid is a versatile hydroxy dicarboxylic acid derivative with a chiral center, offering unique reactivity for fine chemical synthesis. Its structure makes it a valuable building block for creating complex molecules with specific stereochemistry and functional properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators, where its isopropyl and hydroxy groups contribute to biological activity.
• Complexing Agent: Acts as a ligand for metal ions in catalytic systems and in formulations for water treatment or metal surface finishing.
• Polymer Modifier: Incorporated into polyester or polyamide resins to introduce branching points or modify thermal and solubility properties.
• Food & Beverage Additive Precursor: A potential intermediate for synthesizing certain food acidulants or flavor enhancers.
• Cosmetic Ingredient Intermediate: Used in the synthesis of esters or other derivatives that function as skin conditioning agents or emulsifiers.
• Chemical Research & Development: A valuable reagent in organic chemistry labs for methodological studies in asymmetric synthesis and catalysis.

Basic Information

Product Name	2-Hydroxy-2-Isopropylsuccinic Acid
CAS No.	3237-44-3
Molecular Formula	C7H12O5
Molecular Weight	176.17 g/mol
Synonyms	2-Hydroxy-2-(1-methylethyl)butanedioic Acid; 2-Isopropyl-2-hydroxysuccinic Acid; α-Hydroxy-α-isopropylsuccinic Acid; 2-Hydroxy-2-isopropylbutanedioic Acid; 3-Carboxy-2-hydroxy-3-methylpentanedioic Acid (tautomeric form); Hydroxyisopropylsuccinic Acid; (RS)-2-Hydroxy-2-isopropylsuccinic Acid
EINECS	221-795-9

Quality Control

Our 2-Hydroxy-2-Isopropylsuccinic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, impurity profile, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation (Optional)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.