Description

2-Methoxy-4,4,6-Trimethyl-1,3,2-Dioxaborinane is a specialized organoboron reagent, specifically a cyclic boronic ester, valued for its role as a protected boronic acid equivalent in advanced synthetic chemistry. Its primary commercial value lies in enabling efficient cross-coupling reactions, such as Suzuki-Miyaura couplings, while offering improved stability and handling characteristics compared to some boronic acids. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in Suzuki-Miyaura cross-coupling reactions for creating biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific boron-containing motifs.
• Advanced Materials Research: Serves as a precursor in the development of organic electronic materials, including polymers for OLEDs and organic semiconductors.
• Ligand and Catalyst Preparation: Employed in the synthesis of novel boron-based ligands and catalysts for asymmetric synthesis and polymerization processes.
• Chemical Biology & Proteomics: Acts as a reagent for bioconjugation and the development of chemical probes, leveraging boron's unique reactivity.
• Academic & Industrial R&D: A versatile tool for methodological development in organic synthesis and exploring new reaction pathways.

Basic Information

Product Name	2-Methoxy-4,4,6-Trimethyl-1,3,2-Dioxaborinane
CAS No.	3208-69-3
Molecular Formula	C8H17BO3
Molecular Weight	172.03 g/mol
Synonyms	2-Methoxy-4,4,6-trimethyl-1,3,2-dioxaborinane; 4,4,6-Trimethyl-2-methoxy-1,3,2-dioxaborinane; Pinanediol Methylboronate; Methylboronic Acid Pinanediol Ester; (2-Methoxy-1,3,2-dioxaborinan-4-yl)propane (related structural names); Cyclic Methylboronate Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4,4,6-Trimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high chemical purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.