Description

(1S)-(+)-Camphor-10-Sulphonic Acid is a high-purity, enantiomerically pure chiral sulfonic acid derivative of camphor. This compound serves as a versatile and highly valuable chiral resolving agent and catalyst in asymmetric synthesis, enabling the production of optically active intermediates. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemical control is critical.

Application

• Chiral Resolution Agent: Widely used for the separation of racemic mixtures of amines, amino acids, and other basic compounds via diastereomeric salt formation.
• Asymmetric Synthesis Catalyst: Employed as a chiral Brønsted acid catalyst in various organic transformations, including Mannich reactions, aldol condensations, and Diels-Alder reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting the central nervous system, cardiovascular diseases, and more.
• Analytical Chemistry Standard: Used as a reference standard in chiral chromatography (HPLC, GC) for method development and calibration.
• Agrochemical Synthesis: Facilitates the production of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Academic & Industrial Research: A fundamental reagent in research laboratories for developing new synthetic methodologies and studying stereoselective processes.

Basic Information

Product Name	(1S)-(+)-Camphor-10-Sulphonic Acid
CAS No.	3144-16-9
Molecular Formula	C10H16O4S
Molecular Weight	232.30 g/mol
Synonyms	(1S)-(+)-10-Camphorsulfonic Acid; D-(+)-Camphor-10-sulfonic Acid; (1S)-10-Camphorsulphonic Acid; (+)-Camphorsulfonic Acid; (1S)-(+)-Camphorsulfonic Acid; (+)-CSA; D-CSA; (1S,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic Acid
EINECS	221-567-5

Quality Control

Our (1S)-(+)-Camphor-10-Sulphonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high enantiomeric purity and chemical integrity, meeting the stringent requirements for chiral synthesis. Certificates of Analysis (COA) detailing specific purity, chiral purity (enantiomeric excess), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	193°C - 203°C
Specific Rotation [α]20/D	+20° to +22° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.