Description

4,4,4-Trifluoro-2-(4-Fluoro-Phenyl)-3-Oxo-Butyronitrile is a versatile fluorinated organic building block characterized by its trifluoromethyl and cyano ketone functional groups. This compound is highly valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical molecules. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and advanced materials with unique optical or electronic properties.
• Liquid Crystal & OLED Development: Employed in the synthesis of fluorinated components for display and lighting technologies.
• Fluorine Chemistry Research: An important reagent for studying novel fluorination reactions and developing new methodologies in synthetic organic chemistry.

Basic Information

Product Name	4,4,4-Trifluoro-2-(4-Fluoro-Phenyl)-3-Oxo-Butyronitrile
CAS No.	3108-23-4
Molecular Formula	C11H5F4NO
Molecular Weight	243.16 g/mol
Synonyms	4,4,4-Trifluoro-3-oxo-2-(4-fluorophenyl)butanenitrile; 2-(4-Fluorophenyl)-4,4,4-trifluoro-3-oxobutyronitrile; 4-Fluorophenyl trifluoromethyl ketone cyanide; α-(4-Fluorobenzoyl)-α-trifluoromethylacetonitrile; 4,4,4-Trifluoro-2-(p-fluorophenyl)-3-oxobutyronitrile; 3-Oxo-4,4,4-trifluoro-2-(4-fluorophenyl)butyronitrile
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-2-(4-Fluoro-Phenyl)-3-Oxo-Butyronitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.