Description

3-Oxothiobutyric Acid S-Ethyl Ester is a versatile sulfur-containing β-keto ester derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive ketone and a thioester group, makes it an invaluable precursor for constructing complex heterocycles and fine chemicals. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiazole, pyrimidine, and other nitrogen-sulfur heterocycles with potential biological activity.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require specific sulfur-containing motifs.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and functional polymers where the thioester group acts as a modifying agent.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing aroma compounds, contributing to savory or roasted notes.

Basic Information

Product Name	3-Oxothiobutyric Acid S-Ethyl Ester
CAS No.	3075-23-8
Molecular Formula	C6H10O2S
Molecular Weight	146.21 g/mol
Synonyms	S-Ethyl 3-Oxobutanethioate; Ethyl 3-Oxobutanethioate; 3-Oxobutanoic Acid S-Ethyl Ester; Acetoacetic Acid S-Ethyl Ester; Thioacetoacetic Acid Ethyl Ester; Ethyl Thioacetoacetate; 1-(Ethylsulfanyl)butane-1,3-dione
EINECS	221-350-5

Quality Control

Our 3-Oxothiobutyric Acid S-Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.