Description

2,3,4-Tri-o-Acetyl-β-D-Ribopyranosyl Bromide is a key acetylated glycosyl bromide derivative, serving as a vital synthetic intermediate in organic and medicinal chemistry. Its primary value lies in its role as a versatile glycosyl donor for the stereoselective construction of complex carbohydrate structures and nucleoside analogs. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing novel antiviral agents, nucleoside-based therapeutics, and complex glycoconjugates.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Glycochemistry Research: Used as a glycosyl donor in the stereoselective synthesis of complex oligosaccharides and glycoconjugates for biological studies.
• Carbohydrate Chemistry: A fundamental reagent for constructing ribose-containing molecules and studying glycosylation mechanisms.
• Bioconjugation: Employed in the preparation of labeled sugars or carbohydrate-protein conjugates for diagnostic and therapeutic applications.
• Fine Chemical Synthesis: Serves as a precursor for specialty chemicals, chiral ligands, and other high-value synthetic targets.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-β-D-Ribopyranosyl Bromide
CAS No.	3068-30-2
Molecular Formula	C11H15BrO7
Molecular Weight	339.14 g/mol
Synonyms	1-Bromo-2,3,4-tri-O-acetyl-β-D-ribopyranose; β-D-Ribopyranosyl bromide, 2,3,4-triacetate; 2,3,4-Tri-O-acetyl-β-D-ribopyranosyl bromide; 1-Bromo-2,3,4-tri-O-acetyl-D-ribopyranose; Triacetylribosyl bromide; Acetylated ribosyl bromide; β-D-Ribopyranose, 1-bromo-2,3,4-triacetate
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-β-D-Ribopyranosyl Bromide is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems support development from non-GMP research to GMP-grade material for preclinical and clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total impurities ≤ 3.0%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.