Description

Methyl 2-Keto-L-Gulonate is a key chiral intermediate in organic synthesis, particularly valued for its role in the production of L-ascorbic acid (Vitamin C). This compound matters for manufacturers seeking high-purity, reliable building blocks for complex pharmaceutical and nutraceutical synthesis. It is primarily needed by producers in the pharmaceutical, food & beverage, and cosmetic industries for applications requiring precise stereochemistry and consistent quality.

Application

• Primary Intermediate for Vitamin C Synthesis: A crucial precursor in the Reichstein and modern fermentation processes for manufacturing L-ascorbic acid.
• Pharmaceutical Active Ingredient (API) Synthesis: Used as a chiral synthon in the production of various pharmaceutical compounds.
• Nutraceutical and Dietary Supplement Production: Essential for the commercial-scale manufacturing of high-grade Vitamin C used in supplements.
• Food and Beverage Fortification: Serves in the production chain for food-grade Vitamin C used as a preservative and nutrient additive.
• Cosmetic and Personal Care Ingredients: Utilized in synthesizing Vitamin C derivatives (like ascorbyl palmitate) for skincare products.
• Biochemical Research: Employed in enzymatic studies and metabolic pathway research related to carbohydrate chemistry.
• Fine Chemical Synthesis: Acts as a starting material for other specialty sugars and organic compounds.

Basic Information

Product Name	Methyl 2-Keto-L-Gulonate
CAS No.	3031-98-9
Molecular Formula	C7H12O7
Molecular Weight	208.17 g/mol
Synonyms	Methyl L-xylo-2-hexulosonate; Methyl 2-keto-L-gulonate; 2-Keto-L-gulonic acid methyl ester; L-Gulonic acid, 2-keto-, methyl ester; Methyl (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate; Methyl 2-oxo-L-gulonate; Vitamin C intermediate
EINECS	221-212-9

Quality Control

Our Methyl 2-Keto-L-Gulonate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical tests including HPLC, chiral analysis, and residual solvent screening. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-17.0° to -19.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.