Description

3,3-Bis(Trifluoromethyl)-3H-Diazirine is a highly reactive, trifluoromethylated diazirine compound, valued for its role as a versatile photolabile carbene precursor. Its unique structure enables efficient photoaffinity labeling and cross-linking in advanced materials and biochemical research. This compound is essential for R&D and production in pharmaceuticals, agrochemicals, and specialty polymer synthesis.

Application

• Photoaffinity Labeling (PAL): A critical reagent for mapping biomolecular interactions and identifying drug targets in pharmaceutical research.
• Surface Modification & Polymer Cross-linking: Used to introduce fluorinated, reactive groups onto polymer backbones and material surfaces to alter properties like hydrophobicity and chemical resistance.
• Organic Synthesis Intermediate: Serves as a key building block for synthesizing complex fluorinated molecules in medicinal and agrochemical chemistry.
• Bioconjugation & Probe Development: Enables the creation of stable covalent bonds in the development of diagnostic probes and bioconjugates under mild, light-induced conditions.
• Materials Science Research: Employed in the development of novel fluorinated materials, coatings, and adhesives with enhanced performance characteristics.

Basic Information

Product Name	3,3-Bis(Trifluoromethyl)-3H-Diazirine
CAS No.	3024-50-8
Molecular Formula	C3HF6N2
Molecular Weight	194.04 g/mol
Synonyms	3,3-Bis(trifluoromethyl)diaziridine; 3,3-Bis(trifluoromethyl)diazirine; 3H-Diazirine, 3,3-bis(trifluoromethyl)-; Perfluoro-tert-butyl diazirine; Trifluoromethyl Diazirine; Photoaffinity Labeling Reagent; Carbene Precursor; TFD
EINECS	Contact for details

Quality Control

Our 3,3-Bis(Trifluoromethyl)-3H-Diazirine is produced and tested under stringent quality management protocols. Each batch is analyzed to ensure high purity and consistency, with specifications tailored to research and industrial application requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile and light-sensitive nature, it is recommended to store the product at 2-8°C for extended stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.