Description

4'-Fluorochalcone is a high-purity fluorinated chalcone derivative, a key organic building block characterized by its α,β-unsaturated ketone structure. This compound matters for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging its bioactivity as a lead structure.
• Organic Synthesis Building Block: Serves in Michael additions, cyclization reactions, and as a scaffold for creating libraries of fluorinated compounds in medicinal chemistry.
• Material Science Precursor: Employed in the research and development of advanced organic electronic materials and non-linear optical (NLO) materials.
• Biochemical Probe Development: Utilized in academic and industrial research to study enzyme inhibition and biological pathway modulation.
• Flavonoid Analog Synthesis: Acts as a key intermediate for synthesizing fluorinated analogs of natural flavonoids for enhanced stability and bioavailability studies.

Basic Information

Product Name	4'-Fluorochalcone
CAS No.	399-10-0
Molecular Formula	C15H11FO
Molecular Weight	226.25 g/mol
Synonyms	1-(4-Fluorophenyl)-3-phenyl-2-propen-1-one; (E)-1-(4-Fluorophenyl)-3-phenylprop-2-en-1-one; 4-Fluorochalcone; p-Fluorochalcone; 3-Phenyl-1-(4-fluorophenyl)-2-propen-1-one; 2-Propen-1-one, 1-(4-fluorophenyl)-3-phenyl-; FCh; 4-FC
EINECS	Contact for details

Quality Control

Our 4'-Fluorochalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.