Description

4-[(3-Fluorophenyl)Methylene]-2-Phenyloxazol-5(4H)-One is a specialized heterocyclic organic compound featuring an oxazolone core substituted with fluorinated and phenyl groups. This molecular structure makes it a valuable and versatile building block (synthon) and key intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in developing new active ingredients for herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental stability.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Essential for synthetic methodology development and fundamental research in heterocyclic and fluorine chemistry at universities and CROs.

Basic Information

Product Name	4-[(3-Fluorophenyl)Methylene]-2-Phenyloxazol-5(4H)-One
CAS No.	397-62-6
Molecular Formula	C16H10FNO2
Molecular Weight	267.26 g/mol
Synonyms	4-[(3-Fluorobenzylidene)]-2-phenyl-4,5-dihydrooxazol-5-one; 2-Phenyl-4-(3-fluorobenzylidene)-5(4H)-oxazolone; 4-(3-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one; 5(4H)-Oxazolone, 4-[(3-fluorophenyl)methylene]-2-phenyl-; 3-Fluorobenzylidene 2-phenyl-5-oxazolone; Fluorinated oxazolone derivative; CAS 397-62-6
EINECS	Contact for details

Quality Control

Our production of 4-[(3-Fluorophenyl)Methylene]-2-Phenyloxazol-5(4H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.