Description

5-Chloro-3-Fluorosalicylaldehyde is a versatile halogenated salicylaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and fluoro substituents on the aromatic ring, makes it a highly valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the chloro and fluoro groups enhance biological activity and stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Functional Material Precursor: Serves as a starting material for synthesizing organic electronic materials, dyes, and photostabilizers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical reactions and creating compound libraries.
• Fluorescent Probe Synthesis: Used in the construction of fluorophores and molecular probes for biochemical sensing and imaging applications.

Basic Information

Item	Detail
Product Name	5-Chloro-3-Fluorosalicylaldehyde
CAS No.	394-96-7
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	3-Fluoro-5-chlorosalicylaldehyde; 2-Hydroxy-5-chloro-3-fluorobenzaldehyde; 5-Chloro-3-fluoro-2-hydroxybenzaldehyde; Salicylaldehyde, 5-chloro-3-fluoro-; 5-Chloro-3-fluorosalicylaldehyde; 394-96-7; 5-Chloro-3-fluoro-2-hydroxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluorosalicylaldehyde is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation by IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.