Description

1-(3-Bromo-5-Fluoro-2-Hydroxy-Phenyl)-Ethanone is a high-purity, halogenated aromatic ketone building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, offering precise reactivity for selective functionalization. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, cross-coupling reactions, and exploring new synthetic pathways.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value fine chemicals and flavors & fragrances.

Basic Information

Product Name	1-(3-Bromo-5-Fluoro-2-Hydroxy-Phenyl)-Ethanone
CAS No.	393-62-4
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	3'-Bromo-5'-fluoro-2'-hydroxyacetophenone; 1-(3-Bromo-5-fluoro-2-hydroxyphenyl)ethan-1-one; 2-Acetyl-6-bromo-4-fluorophenol; 3-Bromo-5-fluoro-2-hydroxyacetophenone; 2-Hydroxy-3-bromo-5-fluoroacetophenone; 393-62-4; Ethanone, 1-(3-bromo-5-fluoro-2-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-Fluoro-2-Hydroxy-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.