Description

6-Fluoro-1-Phenyl-1,2,3-Benzotriazole is a specialized fluorinated benzotriazole derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a benzotriazole scaffold with fluorine and phenyl substituents, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor or functional additive in the development of advanced organic electronic materials, such as OLEDs or photostabilizers.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems, benefiting from the coordinating properties of the benzotriazole moiety.
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent tags or photoaffinity labels used in proteomics and cellular imaging studies.

Basic Information

Product Name	6-Fluoro-1-Phenyl-1,2,3-Benzotriazole
CAS No.	389-44-6
Molecular Formula	C₁₂H₈FN₃
Molecular Weight	213.21 g/mol
Synonyms	1-Phenyl-6-fluorobenzotriazole; 6-Fluoro-1-phenylbenzotriazole; 6-Fluoro-1-phenyl-1H-benzotriazole; 1-Phenyl-6-fluoro-1H-benzotriazole; 389-44-6; 6-Fluoro-1-phenyl-benzo[1,2,3]triazole; NSC 406911; Benzo[1,2,3]triazole, 6-fluoro-1-phenyl-
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-1-Phenyl-1,2,3-Benzotriazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the exacting standards required for research and cGMP manufacturing, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.