Description

2,2'-Difluorobiphenyl is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique structure, which provides a rigid, electron-deficient aromatic core essential for creating sophisticated materials and active pharmaceutical ingredients. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing new products and processes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to enhance the thermal stability, chemical resistance, and dielectric properties of high-performance engineering plastics and resins.
• Ligand & Catalyst Precursor: Utilized in organometallic chemistry to create specialized ligands for catalysis and material science applications.
• General Organic Synthesis: A versatile fluorinated building block for academic and industrial research in cross-coupling reactions and other transformative chemical processes.

Basic Information

Product Name	2,2'-Difluorobiphenyl
CAS No.	388-82-9
Molecular Formula	C12H8F2
Molecular Weight	190.19 g/mol
Synonyms	2,2'-Difluorodiphenyl; Biphenyl, 2,2'-difluoro-; 2-Fluoro-2'-fluorobiphenyl; o,o'-Difluorobiphenyl; 1,1'-Biphenyl, 2,2'-difluoro-; 2,2'-Difluoro-1,1'-biphenyl; [1,1'-Biphenyl]-2,2'-diol, 2,2'-difluoro derivative
EINECS	Contact for details

Quality Control

Our 2,2'-Difluorobiphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.