Description

Ethanone, 2-Bromo-1-(4-Fluoro-1-Naphthalenyl)- is a high-purity, specialized brominated and fluorinated aromatic ketone building block. This compound is critical for advanced organic synthesis, offering a unique halogenated naphthalene scaffold for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: A versatile building block for Suzuki, Heck, and other cross-coupling reactions to create complex polycyclic aromatic systems.
• Ligand & Catalyst Development: Employed in the design of novel organometallic catalysts and chelating ligands for asymmetric synthesis.
• Fluorescent Probe Synthesis: Utilized as a core structure for developing naphthalene-based fluorescent dyes and molecular sensors.

Basic Information

Product Name	Ethanone, 2-Bromo-1-(4-Fluoro-1-Naphthalenyl)-
CAS No.	388-31-8
Molecular Formula	C₁₂H₈BrFO
Molecular Weight	267.10 g/mol
Synonyms	2-Bromo-1-(4-fluoronaphthalen-1-yl)ethan-1-one; 1-(4-Fluoro-1-naphthyl)-2-bromoethanone; 2-Bromo-1-(4-fluoro-1-naphthyl)ethanone; 4-Fluoro-1-naphthyl bromomethyl ketone; α-Bromo-4-fluoro-1-naphthyl methyl ketone; 2-Bromo-1-(4-fluoronaphthalen-1-yl)ethanone; Bromo(4-fluoro-1-naphthyl)methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Bromo-1-(4-Fluoro-1-Naphthalenyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP and ISO-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.