Description

4-Fluoroindole is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis and pharmaceutical research. Its core value lies in the strategic introduction of a fluorine atom onto the indole scaffold, enabling the fine-tuning of molecular properties such as metabolic stability, lipophilicity, and binding affinity. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediates: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that benefit from the unique properties of fluorine.
• Material Science: Serves as a precursor for functionalized polymers, organic semiconductors, and advanced dyes with tailored electronic properties.
• Academic & Discovery Chemistry: A valuable reagent for exploring new chemical space, structure-activity relationships (SAR), and novel synthetic methodologies in fluorochemistry.
• Bioconjugation & Probe Development: Utilized in creating fluorescent probes and biochemical tools where the indole fluorophore is modified for specific labeling applications.

Basic Information

Product Name	4-Fluoroindole
CAS No.	387-43-9
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	4-Fluoro-1H-indole; 1H-Indole, 4-fluoro-; 4-Fluorindole; 4-Fluoro-indole; 4-FI; 4-Fluor-1H-indol; 4-Fluoroindol; 4-Fluorindol
EINECS	206-864-3

Quality Control

Our 4-Fluoroindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring the material is suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.