Description

1-(9H-Fluoren-9-Yl)-2,2,2-Trifluoroethanone is a specialized organic building block featuring a fluorenyl group and a trifluoroacetyl moiety. This compound is valued for its unique structural properties, which make it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those requiring the fluorene scaffold for biological activity.
• Agrochemical Research: Used in developing new pesticides and herbicides where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Fluorescent Probe Synthesis: The fluorenyl core makes it useful for constructing molecules used in bioimaging and sensor applications.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical reactions in both university and corporate laboratories.

Basic Information

Item	Detail
Product Name	1-(9H-Fluoren-9-Yl)-2,2,2-Trifluoroethanone
CAS No.	386-83-4
Molecular Formula	C₁₅H₉F₃O
Molecular Weight	262.23 g/mol
Synonyms	9-Fluorenyl Trifluoromethyl Ketone; 9-Trifluoroacetylfluorene; 2,2,2-Trifluoro-1-(9H-fluoren-9-yl)ethanone; 1-(9H-Fluoren-9-yl)-2,2,2-trifluoroethan-1-one; 9-Fluorenyltrifluoromethylketone; α,α,α-Trifluoro-9-fluorenyl Methyl Ketone; 9-(Trifluoroacetyl)fluorene
EINECS	Contact for details

Quality Control

Our 1-(9H-Fluoren-9-Yl)-2,2,2-Trifluoroethanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.