Description

Ethanone, 2,2-Dichloro-2-Fluoro-1-Phenyl- (9Ci) CAS NO 384-66-7 is a specialized halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine and fluorine substituents on the acetyl group, makes it a valuable precursor for synthesizing complex molecules in high-value industries. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated and chlorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and pesticides with enhanced activity and environmental profiles.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation and other reactions to introduce the dichlorofluoroacetyl moiety into aromatic systems.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed coupling reactions.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on reactivity and biological activity.

Basic Information

Product Name	Ethanone, 2,2-Dichloro-2-Fluoro-1-Phenyl- (9Ci)
CAS No.	384-66-7
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2,2-Dichloro-2-fluoroacetophenone; α,α-Dichloro-α-fluoroacetophenone; 1-Phenyl-2,2-dichloro-2-fluoroethanone; 2,2-Dichloro-2-fluoro-1-phenylethanone; Phenyl dichlorofluoro ketone; Dichlorofluoroacetophenone; NSC 404087; F-DCA
EINECS	206-851-5

Quality Control

Every batch of Ethanone, 2,2-Dichloro-2-Fluoro-1-Phenyl- is produced and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.4 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.