Description

1,1,1-Trifluoro-Pentan-2-One is a versatile fluorinated ketone building block with unique chemical reactivity. This compound is valued for its ability to introduce the trifluoromethyl group, a key moiety that can significantly alter the physical, chemical, and biological properties of target molecules. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced stability, bioavailability, or specific performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the metabolically stable trifluoromethyl group to improve drug efficacy and pharmacokinetics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased biological activity and environmental persistence.
• Organic Synthesis Building Block: Employed in various fluorination reactions, Grignard additions, and as a precursor for heterocyclic compounds in fine chemical and academic research.
• Liquid Crystal & Electronic Materials: Serves as a starting material for fluorine-containing compounds used in liquid crystal displays (LCDs) and dielectric materials.
• Specialty Solvent & Reagent: Its properties make it suitable for use as a specialty solvent in certain fluorination processes or as a reagent in analytical chemistry.

Basic Information

Product Name	1,1,1-Trifluoro-Pentan-2-One
CAS No.	383-56-2
Molecular Formula	C5H7F3O
Molecular Weight	140.10 g/mol
Synonyms	1,1,1-Trifluoro-2-pentanone; 2-Pentanone, 1,1,1-trifluoro-; Pentafluoropropylethyl Ketone; TFPO; 3,3,3-Trifluoropropyl Methyl Ketone; Ethyl Trifluoroacetate Homolog
EINECS	206-848-0

Quality Control

Our 1,1,1-Trifluoro-Pentan-2-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from strong acids, bases, and oxidizing agents. Due to its highly volatile nature, keep containers tightly sealed when not in use and handle in accordance with good industrial hygiene and safety practices. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.