Description

2,2-Difluoro-2-Phenylacetamide is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique difluoroacetamide structure adjacent to a phenyl ring makes it a valuable precursor for introducing fluorine atoms into complex molecules, a key strategy for modulating their physical, chemical, and biological properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorine to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for synthesizing fluorinated polymers, liquid crystals, or specialty coatings with unique surface properties.
• Organic Synthesis Reagent: Employed in medicinal and synthetic chemistry for constructing complex molecules via reactions at the amide or difluoromethylene group.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, leveraging the fluorine atoms as spectroscopic or reactivity markers.

Basic Information

Product Name	2,2-Difluoro-2-Phenylacetamide
CAS No.	383-19-7
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	α,α-Difluorophenylacetamide; 2,2-Difluoro-2-phenylethanamide; Phenyl(difluoro)acetamide; NSC 404058; Difluorophenylacetamide; (Difluorophenyl)acetamide; 2-Phenyl-2,2-difluoroacetamide
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-Phenylacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.