Description

3,3,4,4,4-Pentafluorobutan-2-One is a high-purity fluorinated ketone building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a pentafluoroethyl group, makes it a valuable precursor for introducing fluorine atoms into target molecules, thereby modifying their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require reliable, high-quality fluorination reagents.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Acts as a building block for fluorinated liquid crystals and organic semiconductors used in displays and electronic devices.
• Polymer & Surface Modifier: Employed in the synthesis of specialty fluoropolymers or as a surface treatment agent to impart oil, water, and stain repellency.
• Organic Synthesis & Catalysis: A versatile reagent in organic chemistry for constructing complex fluorinated molecules and as a ligand or component in catalytic systems.

Basic Information

Product Name	3,3,4,4,4-Pentafluorobutan-2-One
CAS No.	374-41-4
Molecular Formula	C4H3F5O
Molecular Weight	162.06 g/mol
Synonyms	1,1,1,2,2-Pentafluoropropan-3-one; 3,3,4,4,4-Pentafluoro-2-butanone; Pentafluoroacetone Ethyl Ketone; 1,1,1,2,2-Pentafluoro-3-butanone; Pentafluoroethyl Methyl Ketone; 2-Butanone, 3,3,4,4,4-pentafluoro-; Methyl Pentafluoroethyl Ketone
EINECS	206-786-3

Quality Control

Our 3,3,4,4,4-Pentafluorobutan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.