Description

2-(Trifluoromethyl)-2-Hydroxypropionic Acid is a versatile fluorinated organic acid characterized by its trifluoromethyl and hydroxyl functional groups. This unique structure makes it a valuable intermediate for introducing trifluoromethylated motifs, which are highly sought after for their ability to enhance the metabolic stability and lipophilicity of target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) with improved bioavailability and stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group imparts enhanced activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Incorporated to create specialty polymers with unique surface properties and chemical resistance.
• Catalyst & Ligand Preparation: Employed in the synthesis of novel chiral catalysts and ligands for asymmetric synthesis.
• Chemical Research & Development: A crucial reagent in academic and industrial R&D for exploring new fluorination chemistry and compound libraries.

Basic Information

Product Name	2-(Trifluoromethyl)-2-Hydroxypropionic Acid
CAS No.	374-35-6
Molecular Formula	C4H5F3O3
Molecular Weight	158.08 g/mol
Synonyms	2-Hydroxy-2-(trifluoromethyl)propanoic Acid; 2-(Trifluoromethyl)lactic Acid; α-Hydroxy-α-(trifluoromethyl)propionic Acid; 3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid; TFMPA; TFMHA; Hexafluoroisopropanol carboxylic acid (derivative)
EINECS	206-782-4

Quality Control

Our 2-(Trifluoromethyl)-2-Hydroxypropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive and should be handled under inert atmosphere for critical applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	95 - 100 °C
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.