Description

1-Fluoro-6-Iodohexane is a valuable bifunctional alkyl halide building block, characterized by its terminal fluorine and iodine atoms separated by a six-carbon chain. This unique structure makes it a versatile intermediate for introducing fluorinated segments and enabling further functionalization via halogen exchange or cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular construction for active ingredients, liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates and bioactive molecules, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for creating fluorinated pesticides and herbicides with enhanced environmental persistence and efficacy.
• Liquid Crystal Materials: Acts as a building block for fluorinated mesogens in display technologies due to its ability to modify polarity and intermolecular interactions.
• Polymer & Material Science: Employed in the preparation of fluorinated polymers, surfactants, and surface modifiers to impart oil/water repellency and chemical resistance.
• Cross-Coupling Reactions: The iodine moiety is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Fluorine Chemistry Research: A fundamental reagent for studying nucleophilic substitution reactions and the behavior of ω-haloalkyl fluorides.
• Radiochemistry & Labeling: Potential precursor for the synthesis of compounds where the iodine can be replaced with radioactive isotopes for imaging or therapeutic applications.

Basic Information

Product Name	1-Fluoro-6-Iodohexane
CAS No.	373-30-8
Molecular Formula	C₆H₁₂FI
Molecular Weight	218.06 g/mol
Synonyms	6-Fluoro-1-iodohexane; 1-Iodo-6-fluorohexane; Hexane, 1-fluoro-6-iodo-; 6-Fluorohexyl iodide; ω-Fluorohexyl iodide; F(CH₂)₆I; Fluorohexyl iodide
EINECS	206-767-9

Quality Control

Our 1-Fluoro-6-Iodohexane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and organic halogen content, appropriate chemical storage cabinets are recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/mL
Boiling Point	~85-90°C / 10 mmHg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.