Description

1,6-Difluorohexane is a versatile fluorinated alkane building block with the CAS number 373-29-5. Its primary value lies in its use as a key intermediate for introducing fluorine atoms into more complex molecules, enhancing their properties for advanced applications. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents where fluorine substitution improves metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides, pesticides, and fungicides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Acts as a fluorinated linker or side-chain component in the production of advanced electronic display materials.
• Polymer & Surface Modification: Employed to introduce fluorine into polymers, imparting properties like oil and water repellency, chemical resistance, and low surface energy.
• Solvent & Reaction Medium: Utilized as a specialty fluorinated solvent in sensitive chemical reactions and purification processes.
• Refrigerant & Propellant Formulation: A potential component in the development of next-generation, low-global-warming-potential (GWP) fluorocarbon blends.

Basic Information

Product Name	1,6-Difluorohexane
CAS No.	373-29-5
Molecular Formula	C6H12F2
Molecular Weight	122.16 g/mol
Synonyms	Hexane, 1,6-difluoro-; 1,6-Difluoro-n-hexane; Difluorohexane; 1,6-Difluorohexan; F3C(CF2)3CF3 (Note: This is a common mis-association; correct linear formula is F(CH2)6F); α,ω-Difluorohexane; Hexamethylene difluoride; 1-Fluoro-6-fluorohexane
EINECS	206-771-1

Quality Control

Every batch of 1,6-Difluorohexane is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including Gas Chromatography (GC) and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	0.85 - 0.90 g/mL
Boiling Point	Approx. 115 - 120°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.