Description

1,3,5-Trifluorobenzene is a high-purity fluorinated aromatic building block essential for advanced chemical synthesis. Its unique symmetrical structure and fluorine substituents make it a critical intermediate for developing high-performance materials and active pharmaceutical ingredients. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, pesticides, and fungicides where fluorine atoms improve efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorine-based electronic chemicals used in display technologies.
• Polymer Modification: Incorporated into specialty polymers and resins to enhance thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in organometallic chemistry.
• Nuclear Magnetic Resonance (NMR) Solvent: Utilized as a fluorine-19 NMR reference standard and solvent in spectroscopic analysis.

Basic Information

Product Name	1,3,5-Trifluorobenzene
CAS No.	372-38-3
Molecular Formula	C6H3F3
Molecular Weight	132.08 g/mol
Synonyms	sym-Trifluorobenzene; 1,3,5-Trifluorobenzol; Benzene, 1,3,5-trifluoro-; F3Bz; Trifluorobenzene (1,3,5-); 1,3,5-Trifluorobenzen; NSC 9235; AI3-24200
EINECS	206-748-2

Quality Control

Our 1,3,5-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	1.280 - 1.310 g/mL
Refractive Index (n20/D)	1.400 - 1.410
Related Substances (GC)	Report on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.