Description

4-Fluoro-1-Butanesulfonyl Chloride is a versatile organofluorine building block and sulfonylating agent of significant interest in advanced chemical synthesis. Its value lies in its ability to introduce both a fluoroalkyl chain and a reactive sulfonyl chloride group into target molecules, enabling the creation of complex sulfonamides and sulfonate esters. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Material Science: Serves as a monomer or modifier for creating specialty polymers and surface-active agents with unique properties.
• Chemical Biology & Proteomics: Employed as a labeling reagent or linker for modifying proteins and studying biological pathways.
• Liquid Crystal & Electronic Materials: A precursor for synthesizing fluorinated sulfonate derivatives used in advanced display technologies.
• Custom Synthesis & Contract Manufacturing: A critical reagent for research organizations and CROs/CMOs engaged in bespoke chemical production.

Basic Information

Product Name	4-Fluoro-1-Butanesulfonyl Chloride
CAS No.	372-00-9
Molecular Formula	C₄H₈ClFO₂S
Molecular Weight	174.62 g/mol
Synonyms	1-Butanesulfonyl chloride, 4-fluoro-; 4-Fluorobutane-1-sulfonyl chloride; 4-Fluorobutylsulfonyl chloride; 4-Fluorobutanesulfonyl chloride; γ-Fluorobutanesulfonyl chloride; 372-00-9; Butanesulfonyl chloride, 4-fluoro-
EINECS	206-758-1

Quality Control

Our 4-Fluoro-1-Butanesulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to cGMP and ISO standards ensures reliable and consistent material for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.