Description

2-[(2,2,2-Trifluoroethyl)Amino]Ethanol is a versatile organofluorine building block characterized by its aminoethanol core substituted with a trifluoroethyl group. This molecular structure makes it a valuable intermediate for synthesizing advanced compounds where the introduction of fluorine atoms can dramatically alter physical, chemical, and biological properties. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors. Its utility extends to materials science for creating specialized surfactants and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoroethyl group can improve efficacy and environmental profile.
• Specialty Surfactants & Fluoro-Surfactants: Serves as a precursor for synthesizing high-performance surfactants with unique wetting, leveling, and anti-foaming properties for coatings and electronics.
• Polymer Modification: Incorporated into polymer chains to impart specific characteristics such as oil repellency, chemical resistance, or altered surface energy in advanced materials.
• Ligand & Catalyst Design: Utilized in organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing effect of the fluorine atoms.
• Research & Development: A critical reagent in medicinal chemistry and material science research for exploring new fluorinated compound libraries.

Basic Information

Product Name	2-[(2,2,2-Trifluoroethyl)Amino]Ethanol
CAS No.	371-99-3
Molecular Formula	C4H8F3NO
Molecular Weight	143.11 g/mol
Synonyms	2-[(2,2,2-Trifluoroethyl)amino]ethan-1-ol; N-(2,2,2-Trifluoroethyl)ethanolamine; 2-[(Trifluoroethyl)amino]ethanol; 2-Aminoethanol, N-(2,2,2-trifluoroethyl)-; Ethanol, 2-[(2,2,2-trifluoroethyl)amino]-; 2-Hydroxyethyl(2,2,2-trifluoroethyl)amine; N-2-Hydroxyethyl-2,2,2-trifluoroethylamine
EINECS	206-740-5

Quality Control

Every batch of 2-[(2,2,2-Trifluoroethyl)Amino]Ethanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request. Our quality protocols are designed to support applications requiring high consistency, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Impurity A	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.