Description

1,1-Difluorocyclohexane is a versatile fluorinated organic building block characterized by its unique structural motif. This compound is valued for its role as a key intermediate in the synthesis of more complex fluorinated molecules, leveraging the stability and lipophilicity imparted by the fluorine atoms. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries, as well as by manufacturers of specialty materials and fine chemicals. Its high volatility also makes it a candidate for applications in advanced formulations and specialty solvents.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing the difluoromethylene group.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorination enhances biological activity and environmental stability.
• Material Science Research: Acts as a precursor or modifier in the development of fluorinated polymers, coatings, and specialty materials with unique surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via reactions such as nucleophilic substitution or cross-coupling.
• Specialty Solvent & Formulation: Its properties may be utilized in specialized formulations or as a component in high-performance solvent systems for sensitive chemical processes.
• Ligand & Catalyst Development: Can be used to synthesize novel fluorinated ligands for catalysis or in metal-organic framework (MOF) research.

Basic Information

Product Name	1,1-Difluorocyclohexane
CAS No.	371-90-4
Molecular Formula	C6H10F2
Molecular Weight	120.14 g/mol
Synonyms	Cyclohexane, 1,1-difluoro-; 1,1-Difluorocyclohexane; Difluorocyclohexane; NSC 163045; 1,1-Difluoro-cyclohexane; Cyclohexylidene difluoride
EINECS	206-741-1

Quality Control

Our 1,1-Difluorocyclohexane is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC, HPLC) and spectroscopic methods (NMR, IR), to verify identity and quantify purity and potential impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards and can support customer-specific qualification requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.0 g/mL
Boiling Point	~105-110°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.