Description

4-Fluorobutyric Acid 2-Fluoroethyl Ester is a versatile fluorinated organic building block, valued for its unique reactivity profile conferred by the fluorine atoms and ester functionality. This compound is essential for the synthesis of advanced pharmaceutical intermediates, agrochemicals, and specialty materials where the introduction of fluorine is critical for enhancing metabolic stability, lipophilicity, or biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated alkyl chain or ester moiety.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing their dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorine into polymers, improving chemical resistance, reducing surface energy, and enhancing thermal stability.
• Organic Synthesis Building Block: Utilized in various coupling reactions, esterifications, and nucleophilic substitutions to construct complex fluorinated molecules.
• Fluorinated Surfactant & Lubricant Precursor: Acts as an intermediate in the manufacture of specialty surfactants and high-performance lubricants.

Basic Information

Product Name	4-Fluorobutyric Acid 2-Fluoroethyl Ester
CAS No.	371-29-9
Molecular Formula	C6H10F2O2
Molecular Weight	152.14 g/mol
Synonyms	2-Fluoroethyl 4-fluorobutanoate; 4-Fluorobutanoic Acid 2-Fluoroethyl Ester; 2-Fluoroethyl 4-Fluorobutyrate; Ethanol, 2-fluoro-, 4-fluorobutanoate; Butanoic acid, 4-fluoro-, 2-fluoroethyl ester; 4-Fluorobutyric Acid Fluoroethyl Ester; FBE (common abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Fluorobutyric Acid 2-Fluoroethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.