Description

Benzene, 1-(Phenylethynyl)-4-(Trifluoromethyl)- is a specialized aromatic compound featuring a phenylethynyl group and a trifluoromethyl substituent on the benzene ring. This unique structure makes it a valuable high-purity intermediate for advanced organic synthesis, particularly in the development of pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core component in the synthesis of novel electron-transport or host materials for display and lighting technologies.
• Cross-Coupling Reactions: An essential substrate in Sonogashira, Suzuki, and other palladium-catalyzed coupling reactions to create extended π-conjugated systems.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Benzene, 1-(Phenylethynyl)-4-(Trifluoromethyl)-
CAS No.	370-99-0
Molecular Formula	C15H9F3
Molecular Weight	246.23 g/mol
Synonyms	1-(Phenylethynyl)-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)phenylacetylene; 4-(Trifluoromethyl)phenylethyne; p-(Trifluoromethyl)phenylacetylene; (4-Trifluoromethylphenyl)acetylene; 1-Ethynyl-4-(trifluoromethyl)benzene; 4-Ethynylbenzotrifluoride; 4-(Trifluoromethyl)benzenecarbaldehyde
EINECS	Contact for details

Quality Control

Our Benzene, 1-(Phenylethynyl)-4-(Trifluoromethyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.