Description

2-Amino-4'-Fluoroacetophenone is a versatile fluorinated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a fluoro substituent on the acetophenone core, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Intermediate for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable starting material in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Amino-4'-Fluoroacetophenone
CAS No.	369-43-7
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	1-(4-Fluorophenyl)-2-aminoethanone; 2-Amino-1-(4-fluorophenyl)ethanone; 4'-Fluoro-2-aminoacetophenone; 2-Amino-4'-fluorophenylethanone; 4-Fluoro-2-aminoacetophenone; p-Fluoro-2-aminoacetophenone; 2-Amino-1-(4-fluorophenyl)ethan-1-one
EINECS	206-726-5

Quality Control

Our 2-Amino-4'-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support custom purity requirements for specific applications, including pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.