Description

3-(Trifluoromethyl)Biphenyl is a high-purity, synthetically valuable fluorinated aromatic compound. This versatile intermediate is prized for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device stability.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a building block in cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and optical properties.
• Research & Development: A valuable compound for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	3-(Trifluoromethyl)Biphenyl
CAS No.	366-04-1
Molecular Formula	C13H9F3
Molecular Weight	222.21 g/mol
Synonyms	3-Phenylbenzotrifluoride; [1,1'-Biphenyl]-3-yl-trifluoromethane; m-(Trifluoromethyl)biphenyl; 3-Trifluoromethyl-1,1'-biphenyl; 3-(Trifluoromethyl)-1,1'-biphenyl; 3-Trifluoromethylbiphenyl; m-Trifluoromethylbiphenyl; 3-Trifluoromethyl diphenyl
EINECS	206-681-3

Quality Control

Our 3-(Trifluoromethyl)Biphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets stringent purity and identity specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.