Description

1,1,1-Trifluoro-2,3-Epoxypropane is a versatile fluorinated epoxide building block, valued for its unique trifluoromethyl group and high reactivity. This compound is essential for introducing fluorine-containing moieties into target molecules, significantly altering their physical, chemical, and biological properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced stability, lipophilicity, or bioactivity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the trifluoromethyl group to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances efficacy and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and resins with unique surface properties, chemical resistance, and thermal stability.
• Liquid Crystal & Electronic Chemicals: Employed in the manufacture of fluorinated liquid crystals and dielectric fluids for the electronics and display industries.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial R&D for ring-opening reactions, nucleophilic additions, and the construction of complex fluorinated molecular architectures.

Basic Information

Item	Details
Product Name	1,1,1-Trifluoro-2,3-Epoxypropane
CAS No.	359-41-1
Molecular Formula	C3H3F3O
Molecular Weight	112.05 g/mol
Synonyms	3,3,3-Trifluoro-1,2-epoxypropane; Trifluoromethyloxirane; 1,1,1-Trifluoro-2,3-epoxypropane; 2-(Trifluoromethyl)oxirane; 3,3,3-Trifluoropropylene oxide; TFPO; Oxirane, 2-(trifluoromethyl)-; 1,2-Epoxy-3,3,3-trifluoropropane
EINECS	206-630-9

Quality Control

Every batch of 1,1,1-Trifluoro-2,3-Epoxypropane is produced and tested under a strict quality management system. We ensure high purity and consistent performance through rigorous analytical controls including GC, NMR, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed and handle in a fume hood. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.30 g/mL
Boiling Point	~55-57°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.