Description

Pentafluoroethane Sulfonic Acid CAS NO 354-88-1 is a highly fluorinated sulfonic acid derivative, valued for its exceptional acidity and stability as a superacid catalyst. This compound is a critical reagent and building block in advanced organic synthesis and materials science, offering unique reactivity profiles. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel compounds and high-performance materials.

Application

• Superacid Catalyst: Employed as a powerful, non-oxidizing Brønsted acid catalyst in demanding organic transformations, including alkylations, acylations, and isomerizations where conventional acids fail.
• Pharmaceutical Intermediate: Serves as a key synthon for introducing the pentafluoroethanesulfonyl (PES) group, a valuable moiety in drug discovery for modulating bioavailability and metabolic stability.
• Electrolyte Additive: Used in the formulation of high-performance lithium-ion battery electrolytes to enhance conductivity and improve thermal stability at the electrode interface.
• Polymer Modification: Acts as a monomer or grafting agent for synthesizing fluorinated ionomers and specialty polymers with enhanced chemical resistance and surface properties.
• Surface Treatment & Etching: Applied in the microelectronics and semiconductor industries for precision cleaning and surface activation of sensitive components.
• Laboratory Reagent: A valuable tool in academic and industrial research for mechanistic studies and the development of new catalytic systems.

Basic Information

Product Name	Pentafluoroethane Sulfonic Acid
CAS No.	354-88-1
Molecular Formula	C2HF5O3S
Molecular Weight	200.08 g/mol
Synonyms	Perfluoroethanesulfonic Acid; Pentafluoroethanesulfonic Acid; PFESA; 1,1,2,2,2-Pentafluoroethanesulfonic Acid; Ethanesulfonic Acid, Pentafluoro-; NSC 88915; EINECS 206-577-5; PES Acid
EINECS	206-577-5

Quality Control

Our Pentafluoroethane Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by titration, impurity profiling via HPLC and NMR, and verification of identity (IR). We provide comprehensive Certificates of Analysis (COA) to ensure traceability, purity, and compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This material is hygroscopic (moisture-sensitive) and a strong acid/organic solvent. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Related Substances (HPLC)	≤ 1.0 % total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.