Description

2,2-Difluorobutane is a specialized fluorinated hydrocarbon with the CAS number 353-81-1, valued for its unique chemical structure as a building block in advanced synthesis. This compound is primarily utilized as a key intermediate and reagent in the development of pharmaceuticals, agrochemicals, and novel materials. It is essential for research and production facilities focused on fluorination chemistry, organofluorine compound synthesis, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated moieties for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Organic Synthesis Reagent: Acts as a versatile reagent in laboratory and industrial-scale fluorination reactions and as a precursor for more complex organofluorine compounds.
• Material Science: Employed in the research and development of fluorinated polymers, surfactants, and specialty materials with unique surface properties and chemical resistance.
• Refrigerant & Propellant Research: Investigated as a potential component or precursor in next-generation, low-global-warming-potential (GWP) refrigerants and aerosol propellants.
• Electrolyte Additive: Explored for use as an additive in lithium-ion battery electrolytes to enhance performance and safety characteristics.

Basic Information

Product Name	2,2-Difluorobutane
CAS No.	353-81-1
Molecular Formula	C4H8F2
Molecular Weight	94.10 g/mol
Synonyms	Butane, 2,2-difluoro-; 2,2-Difluorobutane; 1,1-Difluorobutane; Difluorobutane; 353-81-1; NSC 9245; EINECS 206-544-5; 2,2-Difluoro-n-butane
EINECS	206-544-5

Quality Control

Our 2,2-Difluorobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including gas chromatography (GC) and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources, sparks, and open flame. Recommended storage temperature is 2-8°C (refrigerated) to maintain stability and prevent volatility. Keep container tightly sealed when not in use to minimize moisture ingress and evaporation.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	0.85 - 0.90 g/mL
Boiling Point	Approx. 40 - 45°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.