Description

1-Heptyne, 7-Fluoro- is a specialized fluorinated alkyne building block of significant interest in advanced organic synthesis. This compound matters for its unique combination of a terminal alkyne group and a fluorine atom, enabling precise molecular construction and the introduction of fluorinated motifs. Industries requiring high-value chemical intermediates, particularly in pharmaceutical research, agrochemical development, and materials science, need this reagent for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing fluorine to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and advanced organic electronic materials to alter surface properties and electronic characteristics.
• Click Chemistry: The terminal alkyne moiety makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating rapid library synthesis for drug discovery.
• Cross-Coupling Reactions: Acts as a coupling partner in Sonogashira, Heck, and other palladium-catalyzed reactions to build complex molecular architectures.
• Fluorine Chemistry Studies: A valuable tool for academic and industrial research into the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Item	Detail
Product Name	1-Heptyne, 7-Fluoro-
CAS No.	353-15-1
Molecular Formula	C7H11F
Molecular Weight	114.16 g/mol
Synonyms	7-Fluoro-1-heptyne; 7-Fluorohept-1-yne; 1-Heptyne, 7-fluoro-; 7-Fluoroheptyne; Hept-1-yn-7-yl fluoride; Fluoroheptyne
EINECS	Contact for details

Quality Control

Our 1-Heptyne, 7-Fluoro- is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. For customers with specific purity requirements (e.g., >98% or research-grade standards), please contact our technical sales team to discuss custom synthesis and QC protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive alkyne functionality, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize risk of polymerization. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.