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6-Fluorohexyl=Methanesulfonate CAS NO 352-95-4
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CAS No.:352-95-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Fluorohexyl Methanesulfonate is a versatile fluorinated alkylating agent and a key building block in advanced organic synthesis. Its value lies in its ability to introduce a fluorohexyl moiety into target molecules, a critical step for modifying physicochemical properties and enhancing bioactivity. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel compounds.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs to improve metabolic stability and membrane permeability.
- Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine atom enhances biological activity and environmental persistence.
- Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
- Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties for applications in coatings, surfactants, and specialty plastics.
- Positron Emission Tomography (PET) Tracer Precursor: Potential use in radiochemistry for synthesizing 18F-labeled compounds for medical imaging.
- Cross-coupling Reactions: Acts as an electrophile in various metal-catalyzed coupling reactions to form carbon-carbon and carbon-heteroatom bonds.
Basic Information
| Product Name | 6-Fluorohexyl Methanesulfonate |
| CAS No. | 352-95-4 |
| Molecular Formula | C7H15FO3S |
| Molecular Weight | 198.26 g/mol |
| Synonyms | 1-Fluoro-6-(methylsulfonyloxy)hexane; Methanesulfonic acid 6-fluorohexyl ester; 6-Fluoro-1-hexanol methanesulfonate; 6-Fluorohexyl mesylate; Hexane, 1-fluoro-6-(methylsulfonyloxy)-; FHM; 6-Fluorohexyl methanesulphonate |
| EINECS | Contact for details |
Quality Control
Our 6-Fluorohexyl Methanesulfonate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Related Substances (HPLC) | Total impurities ≤ 3.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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