Description

5-Fluoro-1H-Indazole is a versatile fluorinated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials, where the introduction of a fluorine atom can dramatically alter biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Fluorine Chemistry: A fundamental substrate for studying fluorination reactions and developing new synthetic methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	5-Fluoro-1H-Indazole
CAS No.	348-26-5
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	5-Fluoroindazole; 5-Fluoro-1H-indazole; 1H-Indazole, 5-fluoro-; 5-Fluoro-1H-indazole; 348-26-5; 5-Fluoroindazol; 5-Fluorindazol; 5-Fluoro-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.