Description

2-(3-Fluorophenyl)Acetophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the 3-fluorophenyl moiety, which can significantly alter the electronic and steric properties of target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorophenyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where fluorine incorporation improves material properties like chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Friedel-Crafts acylations, and reductions to create complex, fluorinated molecular architectures.

Basic Information

Product Name	2-(3-Fluorophenyl)Acetophenone
CAS No.	347-90-0
Molecular Formula	C14H11FO
Molecular Weight	214.24 g/mol
Synonyms	3'-Fluoroacetophenone; 1-(3-Fluorophenyl)ethanone; 3-Fluoroacetophenone; m-Fluoroacetophenone; 3-Fluorophenyl methyl ketone; 3-Acetylfluorobenzene; 3-Fluoro-1-acetylbenzene; 3-Fluorophenylacetone
EINECS	206-489-5

Quality Control

Our 2-(3-Fluorophenyl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.