Description

2-Bromo-1-(4-Fluorophenyl)Propan-1-One is a versatile and high-value organic building block, a key intermediate in the synthesis of complex molecules. Its precise chemical structure makes it essential for creating active pharmaceutical ingredients (APIs) and advanced agrochemicals, where purity and consistency are critical for efficacy and regulatory compliance. This compound is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used as a key building block for manufacturing advanced pesticides, herbicides, and fungicides, contributing to crop protection solutions.
• Organic Synthesis & Research: Serves as a versatile reagent in academic and industrial R&D labs for constructing complex organic molecules, heterocycles, and novel chemical entities.
• Material Science: Potential intermediate in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-Bromo-1-(4-Fluorophenyl)Propan-1-One
CAS No.	345-94-8
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	2-Bromo-4'-Fluoropropiophenone; 4'-Fluoro-2-Bromopropiophenone; 1-(4-Fluorophenyl)-2-bromopropan-1-one; α-Bromo-4-fluoropropiophenone; p-Fluoro-α-bromopropiophenone; 2-Bromo-1-(4-fluorophenyl)-1-propanone; NSC 404087
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with customer requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.