Description

1-Bromo-2,4-Difluoro-5-Nitrobenzene is a versatile halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro and nitro groups impart specific biological activity.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Specialty Dyes and Pigments: An intermediate in the manufacture of high-performance, light-fast dyes and pigments.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-Bromo-2,4-Difluoro-5-Nitrobenzene
CAS No.	345-24-4
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	2,4-Difluoro-5-nitro-1-bromobenzene; 5-Nitro-1-bromo-2,4-difluorobenzene; 1-Bromo-2,4-difluoro-5-nitrobenzene; 345-24-4; Benzene, 1-bromo-2,4-difluoro-5-nitro-; 2,4-Difluoro-5-nitro-bromobenzene; 5-Nitro-2,4-difluorobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,4-Difluoro-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment ensures material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.