Description

Dimethyl Fluoromalonate is a high-purity fluorinated building block essential for advanced organic synthesis. This compound is valued for its unique reactivity, enabling the efficient introduction of fluorine-containing motifs into complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging fluorine's ability to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Fluorinated Material Precursor: Serves as a monomer or modifier in the development of specialty polymers, coatings, and liquid crystals with unique chemical and thermal resistance.
• Organic Synthesis Reagent: Employed in nucleophilic fluorination reactions, Michael additions, and cyclization processes to construct complex, fluorinated heterocycles and aliphatic chains.
• Chemical Research & Development: A versatile tool in medicinal and process chemistry for exploring structure-activity relationships (SAR) and optimizing synthetic routes.

Basic Information

Product Name	Dimethyl Fluoromalonate
CAS No.	344-14-9
Molecular Formula	C5H7FO4
Molecular Weight	150.10 g/mol
Synonyms	Dimethyl fluoromalonate; Fluoromalonic acid dimethyl ester; Methyl fluoromalonate; Dimethyl 2-fluoromalonate; Propanedioic acid, 2-fluoro-, 1,3-dimethyl ester; 2-Fluoromalonic acid dimethyl ester; DMFM
EINECS	Contact for details

Quality Control

Our Dimethyl Fluoromalonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.