Description

Naphthalene, 1-Bromo-3-Fluoro- is a halogenated naphthalene derivative that serves as a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for introducing both bromine and fluorine substituents into complex molecular architectures, enabling fine-tuning of electronic properties and reactivity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in OLED device fabrication.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated liquid crystals and other specialty electronic chemicals.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A fundamental reagent in academic and industrial labs for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	Naphthalene, 1-Bromo-3-Fluoro-
CAS No.	343-53-3
Molecular Formula	C₁₀H₆BrF
Molecular Weight	225.06 g/mol
Synonyms	1-Bromo-3-fluoronaphthalene; 3-Fluoro-1-bromonaphthalene; 1-Bromo-3-fluoro-naphthalene; Naphthalene, 1-bromo-3-fluoro-; 3-Fluoronaphthalen-1-yl bromide; 1-Brom-3-fluornaphthalin (German); 1-ブロモ-3-フルオロナフタレン (Japanese)
EINECS	Contact for details

Quality Control

Every batch of our 1-Bromo-3-fluoronaphthalene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all commercial quantities and are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.