Description

1-Bromo-2-Fluoronaphthalene is a high-purity halogenated naphthalene derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the naphthalene ring, enabling precise functionalization and the creation of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the naphthalene core provides a stable scaffold for bioactive molecules.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or host materials in OLED displays and lighting due to its rigid, planar structure.
• Liquid Crystal & Functional Material Research: Employed in creating novel liquid crystal compounds and organic semiconductors for electronic applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine substitution on aromatic systems and reaction pathways.

Basic Information

Product Name	1-Bromo-2-Fluoronaphthalene
CAS No.	342-55-2
Molecular Formula	C₁₀H₆BrF
Molecular Weight	225.06 g/mol
Synonyms	2-Fluoro-1-bromonaphthalene; 1-Bromo-2-fluoronaphthalene; Naphthalene, 1-bromo-2-fluoro-; 1-Brom-2-fluornaphthalin; NSC 404058; 1-Bromo-2-fluoronaftaleno; 1-ブロモ-2-フルオロナフタレン
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoronaphthalene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP and research environments where reliable purity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.