Description

5-(Trifluoromethyl)Quinoline is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is crucial for modulating the biological activity and physicochemical characteristics of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who are developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the CF3 group enhances lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional organic compounds for electronic applications.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and the behavior of fluorinated aromatic systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-(Trifluoromethyl)Quinoline
CAS No.	342-30-3
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	5-(Trifluoromethyl)quinoline; Quinoline, 5-(trifluoromethyl)-; 5-Trifluoromethylquinoline; 5-CF3-Quinoline; γ-(Trifluoromethyl)quinoline; 342-30-3; NSC 406925
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.